Dentate gyrus volume deficit in schizophrenia
نویسندگان
چکیده
منابع مشابه
The dentate gyrus: fundamental neuroanatomical organization (dentate gyrus for dummies).
The dentate gyrus is a simple cortical region that is an integral portion of the larger functional brain system called the hippocampal formation. In this review, the fundamental neuroanatomical organization of the dentate gyrus is described, including principal cell types and their connectivity, and a summary of the major extrinsic inputs of the dentate gyrus is provided. Together, this informa...
متن کاملNeurotrophins in the dentate gyrus.
Since the discovery of nerve growth factor (NGF) in the 1950s and brain-derived neurotrophic factor (BDNF) in the 1980s, a great deal of evidence has mounted for the roles of neurotrophins (NGF; BDNF; neurotrophin-3, NT-3; and neurotrophin-4/5, NT-4/5) in development, physiology, and pathology. BDNF in particular has important roles in neural development and cell survival, as well as appearing ...
متن کاملModeling the dentate gyrus.
Computational modeling has become an increasingly useful tool for studying complex neuronal circuits such as the dentate gyrus. In order to effectively apply computational techniques and theories to answer pressing biological questions, however, it is necessary to develop detailed, data-driven models. Development of such models is a complicated process, akin to putting together a jigsaw puzzle ...
متن کاملFusiform gyrus volume reduction and facial recognition in chronic schizophrenia.
BACKGROUND The fusiform gyrus (FG), or occipitotemporal gyrus, is thought to subserve the processing and encoding of faces. Of note, several studies have reported that patients with schizophrenia show deficits in facial processing. It is thus hypothesized that the FG might be one brain region underlying abnormal facial recognition in schizophrenia. The objectives of this study were to determine...
متن کاملReduced left angular gyrus volume in first-episode schizophrenia.
OBJECTIVE Research suggests that the normal left-greater-than-right angular gyrus volume asymmetry is reversed in chronic schizophrenia. The authors examined whether angular gyrus volume and asymmetry were abnormal in patients with first-episode schizophrenia. METHOD Magnetic resonance imaging scans were obtained from 14 inpatients at their first hospitalization for psychosis and 14 normal co...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Psychological Medicine
سال: 2019
ISSN: 0033-2917,1469-8978
DOI: 10.1017/s0033291719001144